Non-Apoptotic Role of Apoptotic Caspases in the Drosophila Nervous System

Non-Apoptotic Role of Apoptotic Caspases in the Drosophila Nervous System

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An increasing number of studies demonstrate that cells can activate apoptotic Dishwasher Door Hinge caspases but not die and, instead, display profound changes in cellular structure and function.In this minireview, we will discuss observations in the nervous system of Drosophila melanogaster that illustrate non-apoptotic roles of apoptotic caspases.We will preface Console Mast Right with Decal these examples with similar observations in other experimental systems and end with a discussion of how apoptotic caspase activity might be constrained to provide non-lethal functions without killing the cell.